David I C Scopes Selected Research

2- fluoro- 5- (5- (3- morpholin- 4- ylphenoxy)pyrimidin- 2- ylamino)benzonitrile

12/2013	Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500.
4/2013	Orally bioavailable small molecule drug protects memory in Alzheimer's disease models.

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David I C Scopes Research Topics

Disease

8	Alzheimer Disease (Alzheimer's Disease) 01/2014 - 01/2009
1	Dementia (Dementias) 01/2014
1	Memory Disorders (Memory Loss) 12/2013
1	Neuroinflammatory Diseases 01/2011
1	Inflammation (Inflammations) 01/2011
1	Gaucher Disease (Gaucher's Disease) 01/2005

Drug/Important Bio-Agent (IBA)

5	Amyloid (Amyloid Fibrils)IBA 01/2014 - 01/2009
3	Amyloid beta-PeptidesIBA 04/2013 - 01/2009
2	Peptides (Polypeptides)IBA 12/2013 - 01/2009
2	2- fluoro- 5- (5- (3- morpholin- 4- ylphenoxy)pyrimidin- 2- ylamino)benzonitrileIBA 12/2013 - 04/2013
1	SEN1576IBA 01/2014
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	pyrimidineIBA 01/2011
1	SEN1176IBA 01/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2011
1	Interleukin-6 (Interleukin 6)IBA 01/2011
1	GlycosyltransferasesIBA 01/2005
1	ceramide glucosyltransferaseIBA 01/2005
1	EnzymesIBA 01/2005

Therapy/Procedure

1	Oral Administration 04/2013
1	Injections 01/2011
1	Therapeutics 01/2009